Prof. C.N.R.A. Alles
Professor in Biochemistry
 
International Peer Reviewed Publications
  1. A pilot study on attitudes, knowledge and behaviour towards dental diseases among grade medical officers in Kandy district, Sri Lanka. Soysa NS, Alles N. The Journal of Dentist. 2016: Article in press.

  2. The polyethylene glycol crosslinking of cholesterol-bearing pullulan nanogels increased the inhibitory effects of the W9 synthetic peptide on bone loss in a murine bone resorption model. Toshimi Sato, Neil Alles, Masud Khan, Kenichi Nagano, Maroko Takahashi, Yukihiko Tamura, Asako Shimoda, Keiichi Ohya, Kazunari Akiyoshi, Kazuhiro Aoki. International Journal of Nanomedicine. 2015:10 3459–3473. Journal impact factor: 4.195

  3. NF-?B RELA-deficient bone marrow macrophages fail to support bone formation and to maintain the hematopoietic niche after lethal irradiation and stem cell transplantation. Setsuko Mise-Omata, Neil Alles, Taro Fukazawa, Kazuhiro Aoki, Keiichi Ohya, Eijiro Jimi, Yuichi Obata and Takahiro Doi. International Immunology. 2014;26(11):607-18. Journal impact factor: 3.181

  4. Gelatin hydrogel carrier with the W9-peptide elicits synergistic effects on BMP-2-induced bone regeneration. Md. AbdullahAlMamun, Md.AbdullaAlMasudKhan, Neil Alles, MakotoMatsui, YasuhikoTabata, KeiichiOhya, KazuhiroAoki. Journal of Oral Biosciences. 2013: 55:217-23

  5. Disruption of NF-kB1 prevents bone loss caused by mechanical unloading. Nakamura H, Aoki K, Masuda W, Alles N, Nagano K, Fukushima H, Osawa K, Yasuda H, Nakamura I, Mikuni-Takagaki Y, Ohya K, Maki K, Jimi E. J Bone Miner Res. 2013;28(6):1457-67. Journal impact factor: 7.056

  6. A small peptide inhibitor of inflammatory bone resorption promotes BMP-2- induced bone formation. Abdulla Al Masud Khan, Neil Alles, Niroshani S. Soysa, Md. Abdullah Al Mamun, Kenichi Nagano, Risako Mikami, Yuriko Furuya, Hisataka Yasuda, Keiichi Ohya, KazuhiroAoki. Journal of Oral Biosciences. 2013;55(1):47-54.

  7. Osteoclast formation and differentiation; an overview. Soysa NS, Alles N*, Aoki K, Ohya K. J Med Dent Sci. 2012;59(3):65-74. * Corresponding Author

  8. Peptide-based delivery to bone. Aoki K, Alles N, Soysa NS, Ohya K. Adv Drug Deliv Rev. 2012;64(3):1220-38. Journal impact factor: 14.608

  9. A structural modulator of tumor necrosis factor type 1 receptor promotes bone formation under lipopolysaccharide-induced inflammation in a murine tooth extraction model. Nakachi H, Aoki K, Tomomatsu N, Alles N, Nagano K, Yamashiro M, Zhang H, Murali R, Greene MI, Ohya K, Amagasa T.European Journal of Pharmacology. 2012; 697(1-3):132-8. Journal impact factor: 2.728

  10. Suppression of NF-kappaB increases bone formation and ameliorates osteopenia in ovariectomized mice. Alles N, Soysa NS, Hayashi J, Khan M, Shimoda A, Shimokawa H, Ritzeler O, Akiyoshi K, Aoki K, Ohya K. Endocrinology. 2010;151(10):4626-34. Journal impact factor: 4.459

  11. The Pivotal Role of the Alternative NF-kappaB Pathway in Maintenance of Basal Bone Homeostasis and Osteoclastogenesis. Soysa NS, Alles N, Weih D, Lovas A, Mian AH, Shimokawa H, Yasuda H, Weih F, Jimi E, Ohya K, Aoki K. J Bone Miner Res. 2010;25(4):809-18.Journal impact factor: 7.056
    *Soysa NS and Alles N contributed equally.
    **Received a commendation from Faculty of 1000 which is an award-winning online service that highlights and evaluates the most interesting papers published in the biological sciences.

  12. Polysaccharide nanogel delivery of a TNF-alpha and RANKL antagonist peptide allows systemic prevention of bone loss. Alles N, Soysa NS, Hussain MD, Tomomatsu N, Saito H, Baron R, Morimoto N, Aoki K, Akiyoshi K, Ohya K. Eur J Pharm Sci. 2009 ;37(2):83-8. Journal impact factor: 3.536

  13. The tumor necrosis factor type 2 receptor plays a protective role in tumor necrosis factor- α -induced bone resorption lacunae on mouse calvariae. Nagano K, Alles N, Mian AH, Shimoda A, Morimoto N, Tamura Y, Shimokawa H, Akiyoshi K, Ohya K, Aoki K. J Bone Miner Metab. 2011;29(6):671-81. Journal impact factor: 2.268

  14. Defective NIK in aly/aly mice prevents bone resorption induced by local injection of Lipopolysaccharide. Soysa NS, Alles N, Aoki K, Ohya K. J Perio Res. 2011;46(2):280-4. *Received a commendation from Target Intelligence Service (TIS), a database used by pharmaceutical companies worldwide to identify ground breaking research of relevance to their own work on potential drug targets. Journal impact factor: 1.686

  15. Processing of the NF-kappa B2 precursor p100 to p52 is critical for RANKL-induced osteoclast differentiation. Maruyama T, Fukushima H, Nakao K, Shin M, Yasuda H, Weih F, Doi T, Aoki K, Alles N, Ohya K, Hosokawa R, Jimi E. J Bone Miner Res. 2010;25(5):1058-67. Journal impact factor: 7.056

  16. Increased bone mass in adult prostacyclin-deficient mice. Nakalekha C, Yokoyama C, Miura H, Alles N, Aoki K, Ohya K, Morita I. J Endocrinol. 2010;204(2):125-33. Journal impact factor: 3.568

  17. Three-dimensional characterization of osteoclast bone-resorbing activity in the resorption lacunae. Soysa NS, Alles N, Aoki K, Ohya K. J Med Dent Sci. 2009 ;56(3):107-12.

  18. Inhibition of the classical NF-kappaB pathway prevents osteoclast bone-resorbing activity. Soysa NS, Alles N, Shimokawa H, Jimi E, Aoki K, Ohya K. J Bone Miner Metab. 2009;27(2):131-9. Journal impact factor: 2.268

  19. NF-kappaB functions in osteoclasts. Soysa NS, Alles N. Biochem Biophys Res Commun. 2009 ;378(1):1-5. Journal impact factor: 2.648

  20. LPS-induced inhibition of osteogenesis is TNF-alpha dependent in a murine tooth extraction model. Tomomatsu N, Aoki K, Alles N, Soysa NS, Hussain A, Nakachi H, Kita S, Shimokawa H, Ohya K, Amagasa T. J Bone Miner Res. 2009;24(10):1770-81.Journal impact factor: 7.056

  21. Lipopolysaccharide-induced bone resorption is increased in TNF type 2 receptor-deficient mice in vivo. Hussain Mian A, Saito H, Alles N, et al. J Bone Miner Metab. 2008; 26:469-77.Journal impact factor: 2.268

  22. Defective microtubule-dependent podosome organization in osteoclasts leads to increased bone density in Pyk2 (-/-) mice. Gil-Henn H, Destaing O, Sims NA, Aoki K, Alles N, et al. J Cell Biol. 2007; 178:1053-64.Journal impact factor: 12.480

  23. Three-Dimensional Measurements of Bone Resorption Lacunae Reveal Inhibition of Osteoclast Activity by TNF-a Antagonist In Vitro. Hiroaki Saito, Niroshani Soysa, Neil Alles, Kazuhiro Aoki, Keiichi Ohya. Dentistry in Japan. 2006;42: 33-37.
Local Publications
  1. Stress: A friend or foe? Soysa NS, Alles N. The General Dental Practitioner. 2014;31:38-41.

  2. Prevalence of Candida in saliva and root canals of teeth associated with apical periodontitis. Soysa NS, Fernando HN, Alles N, Wijeyeweera RL, Wettasinghe KA, Panagoda GJ. Sri Lanka Dental Journal 2010;40(02-03):54-60
International Journal Abstracts
  1. LPS causes early local bone-resorption and increases bone mineral density in mice. N. Soysa, N. Alles, K. Aoki and K. Ohya. Journal of Dental Research. 2013

  2. Both TNF- α and RANKL antagonist peptide stimulates bone formation in TNF- α deficient mice to the same extent as in wild type mice. M Khan, N Alles, Furuya Y, Yasuda H, Ohya K, Aoki K. Journal of Bone Mineral Reserch. 2011.

  3. Pharmacological inhibition of NF-kB for bone formation in vitro and in vivo. NS Soysa, N Alles, J Hayashi, M Khan, A Shimoda, H Shimokawa, O Ritzeler, K. Akiyoshi, K Aoki, K Ohya. Journal of Dental Research. 2010.

  4. NF-kB–inducing kinase is necessary for LPS-induced bone resorption. N Alles, N Soysa, K Akiyoshi, K Aoki, K Ohya Journal of Dental Research. 2009.
  5. Defective alternative pathway of NF-kB causes mild osteopetrosis in mice. N Soysa, N Alles, K Aoki, H. Shimokawa, E Jimi, K Ohya. Journal of Dental Research. 2008.

  6. The inhibitory role of TNF-a release by LPS in the osteogenesis after tooth extraction in vivo. N. Tomomatsu, K.Aoki, M. A. Hussain, C.N.R Alles, K. Aoki, K. Ohya, K. Amagasa. Journal of Bone Mineral Research. 2008

  7. Inhibition of IKKb-NEMO binding blocks osteoclast activity and actin-ring formation. N.Soysa, C.Alles, H. Saito, K.Aoki, E.Jimi, K.Ohya. Journal of Dental Research. 2006.

  8. Canonical NF-kB pathway mediates Osteoclast Bone resorption activity.　 N.S Soysa, C.N.R Alles, K Aoki, E Jimi, K Ohya. Journal of Bone Mineral Research. 2007:22:254.

  9. Use of Nanogels as a drug delivery system for tumor necrosis factor-alpha antagonist in murine bone resorption model. C.N.R Alles, A.H Mian, N.S Soysa, H.Saito, K.Aoki, K.Akiyoshi, K.Ohya. Journal of Bone Mineral Research. 2007:22:153.

  10. TNFR1 and 2 differentially regulates inflammatory bone resorption induce by LPS in vivo. M.H Mian, K Aoki, N Alles, K. Aoki, K. Ohya. Bone Mineral Research. 2007:22.

  11. Subcutaneous injection of W9 peptide and CHP nanogel complex inhibits the decrease of BMD induced by a low Ca feeding in mice. C.N.R.A Alles, N.Morimoto, U.Hasegawa, A.Mian, N.S. Soysa, H. Saito, K.Aoki, R.Baron, K.Akiyoshi, K.Ohya. Journal of Bone Mineral Research. 2006: 21: 396.
Presentations at International scientific meetings
  1. Pilot study on attitudes, knowledge and behaviour towards dental diseases among grade medical officers in Kandy district, Sri Lanka. N.R. A. Alles, T. Dissanayake, K. Rathnayake, N.S. Soysa (2015) .World Dental Federation, Annual World Dental Congress (FDI), Bangkok, Thailand.

  2. Assessment of soluble fluoride concentrations in fluoridated tooth pastes marketed in Sri Lanka. N.S. Soysa, N. Alles (2015) .World Dental Federation, Annual World Dental Congress (FDI), Bangkok, Thailand.

  3. Availability of total, soluble and ionic fluoride concentration in commonly used dentifrices in Sri Lanka. N.S. Soysa, N. Alles, L. Tenuta, J. Cury (2015) .Asia Pacific Dental Congress (APDC), Singapore.

  4. Elucidation of the relationship between a bone turnover marker, CTX, and some trace minerals. G.K. M. Godakumara, E.G.C.N. Premathilake, N. Alles, P. H. P. Fernando, N.S. Soysa (2015). Annual research session-University of Peradeniya, Sri Lanka (iPURSE).

  5. Pilot study on changes in some trace elements in long bones in ovariectomized mice. E.G.C.N. Premathilake, G.K.M. Godakumara, P. H. P. Fernando, N. Alles, N.S. Soysa (2015). Annual research session-University of Peradeniya, Sri Lanka (iPURSE).

  6. Quantitative analysis of micromineral contents in six specieses of marine macro algae – a preliminary study. L.A. wanasinghe, E.G.C.N. Premathilake, P. H. P. Fernando, N. Alles, M.C.N. Perera, W.D.M.C. Wickramanayake, R.P.V.J. Rajapakse (2015). Annual research session-University of Peradeniya, Sri Lanka (iPURSE).

  7. Metachromatic activity of some species of marine macro algae found in the southern Sri Lankan coast. L.A. wanasinghe, P. H. P. Fernando, N. Alles, A.M.P.S.T. Bandara, R.P.V.J. Rajapakse (2015). Annual research session-University of Peradeniya, Sri Lanka (iPURSE).

  8. Rankl-antagonist-peptide increases bone formation in vitro and in vivo. N. Alles, N.S. Soysa, P. H. P. Fernando, K. Ohya, K. Auki (2014). Annual research session-University of Peradeniya, Sri Lanka (iPURSE).

  9. Local administration of LPS on calvariae cause delayed effect on bone mineral density in long bones of mice. N.S Soysa, N. Alles, K. Aoki and K. Ohya (2013). DI/CDA/SLDA Joint International Conference, Colombo, Sri Lanka.

  10. LPS causes early local bone-resorption and increases bone mineral density in mice. N. Soysa, N. Alles, K. Aoki and K. Ohya (2013). 91st General Session and Exhibition of International Association for Dental research (IADR), Seattle, USA

  11. Disruption of NF-?B1 prevents bone loss caused by mechanical unloading. Nakamura H, Aoki K, Masuda W, Alles N, Nagano K, Fukushima H, Osawa K, Yasuda H, Nakamura I, Mikuni-Takagaki Y, Ohya K, Maki K, Jimi E. J Bone Miner Res. 2013;28(6):1457-67.

  12. The local administration of TNF-? and RANKL antagonist peptide promotes BMP-2-induced bone formation. Abdulla Al Masud Khan, Neil Alles, Niroshani S. Soysa, Md. Abdullah Al Mamun, Kenichi Nagano, Risako Mikami, Yuriko Furuya, Hisataka Yasuda, Keiichi Ohya, Kazuhiro Aoki. Journal of Oral Biosciences. 2013;55:47-54.

  13. Gelatin hydrogel carrier with the W9-peptide elicits synergistic effects on BMP-2-induced bone regeneration. Md. Abdullah Al Mamun, Md. Abdulla Al Masud Khan, Neil Alles, Makoto Matsui, Yasuhiko Tabata, Keiichi Ohya, Kazuhiro Auki. Journal of Oral Biosciences. 2013;55:217-223

  14. Bone resorption inhibitory peptide repairs critical size defect on calvariae in mice. N Alles, N Soysa, M Khan, Ohya K, Aoki K. (2012) Journal of Bone Mineral Reserch.

  15. RANKL-Mediated Bone Formation By TNF-alpha Antagonist Peptide. M. Khan, N. Alles, A. Mamun, K. Nagano, K. Ohya, and K. Aoki (2012) Journal of Dental Research.

  16. TNF- α antagonist peptide increases ectopic bone formation under RANKL dependent Mechanism. M Khan, N Alles, M Mamun et al. (2012). 29th Annual Meeting of Japanese Association of bone mineral Research, Niigata, Japan

  17. An antagonist of tumor necrosis factor-a stimulates bone formation under the lipopolysaccharide induced inflammation in a murine tooth extraction model. Kazuhiro Aoki, Hiroyuki Nakachi, Neil Alles et al. (2012). Annual Meeting of the Japanese Pharmacological Society (JPS), Kyoto, Japan

  18. BMP and gelatin carrier induced local bone formation. Mamun A. A, Khan M, Alles N, Ohya K, Aoki K (2012).The 54th Annual Meeting of The Japanese Society of Oral biology, Koriyama, Japan.

  19. Both TNF- α and RANKL antagonist peptide stimulates bone formation in TNF- α deficient mice to the same extent as in wild type mice. M Khan, N Alles, Y Furuya, et al. (2011). 33rd Annual Meeting of American Society for Bone and Mineral Research (ASBMR), San Diego, USA.

  20. A bone resorption inhibitor promotes bone formation. M Khan, N Alles, H Yasuda, et al. (2011). 59th Annual Meeting of Japanese Association for Dental Research, Hiroshima, Japan.

  21. TNF- α antagonist peptide stimulates bone formation under TNF- α independent mechanism. M Khan, N Alles, K Nagano et al. (2011). 29th Annual Meeting of Japanese Association of bone mineral Research,Osaka, Japan.

  22. The stimulatory effects of TNF- α and RANKL antagonist peptide W9 on bone formation. M Khan, N Alles, K Nagano et al. (2011). 31st Annual Meeting of the Japanese Society for Bone morphometry. Gifu, Japan.

  23. The stimulatory effects of NFkB inhibitor on bone formation. Kazuhiro Aoki, Masud Khan, Neil Alles, et al. (2011). Annual Meeting of the Japanese Pharmacological Society (JPS), Yokohama, Japan

  24. Pharmacological Inhibition of NF-kB For Bone Formation In vitro And In vivo. NS. Soysa , N Alles , J Hayashi et al. (2010). 88th General Session and Exhibition of International Association for Dental research (IADR), Barcelona, Spain.

  25. The effect of anti-bone resorption peptide with nanogel sheet as a peptide carrier: comparison to a nanogel cross-linking hydrogel. K Aoki, N Alles, M Khan et al. (2010), Osaka, Japan.

  26. The control release of TNF-a is necessary to mimic LPS-induced bone resorption on calvaria. Kenchi Nagano, Kazuhiro Aoki, Hussain Mian, Neil Alles et al. (2009). The 82nd Annual Meeting of the Japanese Pharmacological Society (JPS), Yokohama, Japan.

  27. Lack of precursor p100 of NF-kB2 causes osteopenia in mice. Niroshani Soysa, Neil Alles, Kazuhiro Aoki et al. (2009). 29th Annual Meeting of Japanese Society for Bone Morphometry, Osaka, Japan.

  28. NF-kB–inducing kinase is necessary for LPS-induced bone resorption. N Alles, N Soysa, K Aoki, et al. (2009). 87th General Session and Exhibition of International Association for Dental research (IADR), Miami, USA.

  29. Inhibition of IKK-b blocks osteoclast formation and activity. K.Ohya, N Soysa, N Alles, K Aoki. (2009). 57th Annual Meeting of the Japanese Association for Dental Research (JADR), Wuhan, China.

  30. Polysaccharide nanogel delivery of TNF-a antagonist-peptide prevents systemic bone loss. N Alles, N Soysa, N Morimoto, et al (2009). Research Day, Faculty of Dentistry, University of Toronto, Canada.

  31. Defective alternative pathway of NF-kB causes mild osteopetrosis in mice. N Soysa, N Alles, K Aoki, H. Shimokawa, E Jimi , K Ohya (2008). 86th General Session and Exhibition of the International Association for Dental Research (IADR), Toronto, Canada.

  32. NIK mutation in aly/aly mice causes osteopetrosis and reduces RANKL induced osteoclasogenesis. N.S Soysa, C.N.R Alles, AH Mian, H Yasuda, E Jimi , H. Shimokawa, K Aoki, K Ohya (2008). The 2nd International Conference on Osteoimmunology, Rhodes, Greece.

  33. Nanogel cross-linking hydrogel as a drug delivery system for the peptide type of drugs. C.N.R.A Alles, N.S. Soysa, K.Aoki, K.Ohya (2008).The 50th Annual Meeting of the Japanese Society of Oral Biology, Tokyo, Japan.

  34. Non-canonical NF-kB regulates osteoclast formation and function. N.S Soysa, C.N.R Alles, K Aoki, H. Shimokawa, E Jimi, K Ohya (2008).The 81th Annual Meeting of the Japanese Pharmacological Society, Yokohama, Japan.

  35. Nanogel cross-linking hydrogel as a drug delivery system for tumor necrosis factor-alpha antagonist. C.N.R Alles, N.S Soysa, A.H Mian, N. Tomamatsu, N. Morimoto, U. Hasegawa, S. Sawada, Y. Tada, K.Akiyoshi, K.Ohya, K.Aoki (2008).30th Annual Meeting of American Society for Bone and Mineral Research (ASBMR), Montréal, Quebéc, Canada.

  36. The inhibitory role of TNF-a release by LPS in the osteogenesis after tooth extraction in vivo. N. Tomomatsu, K.Aoki, M. A. Hussain, C.N.R Alles , et al. (2008). 30th Annual Meeting of American Society for Bone and Mineral Research (ASBMR), Montréal, Quebéc, Canada.

  37. Defective NIK causes impaired osteoclastogenesis and mild osteopetrosis in mice.　 N.S Soysa, N. Alles, K Aoki, H.Shimokawa, E Jimi, K Ohya (2008). The 55th Annual Meeting of the JADR, Tsurumi, Japan.

  38. Effects of Treadmill running load on bone mass in p50 deficient mice. K. Aoki, H. Fukushima, N. A. Alles, et al. (2008). 26th Annual Meeting of Japanese Society for Bone and Mineral Research (JSBMR), Osaka, Japan.

  39. CHP nanogel and W9 peptide complex ameliorates bone resorption in the low Ca murine model. . C.N.R Alles, A. H. Mian, K Aoki, K Ohya (2008).The 81th Annual Meeting of the Japanese Pharmacological Society, Yokohama, Japan.

  40. Assessing osteoclast function by 3-D measurements of resorption lacunae. N. A. Alles, N. S. Soysa. (2008). Annual research journal of SLSAJ. Tokyo, Japan.

  41. Canonical NF-kB pathway mediates Osteoclast Bone resorption activity. N.S Soysa, C.N.R Alles, K Aoki, E Jimi, K Ohya (2007). 29th Annual Meeting of American Society for Bone and Mineral Research (ASBMR), Hawaii, USA.

  42. TNFR1 and 2 differentially regulates inflammatory bone resorption induce by LPS in vivo. M.H Mian, K Aoki, N Alles, et al (2007). 29th Annual Meeting of ASBMR, Hawaii, USA.

  43. Use of Nanogels as a drug delivery system for tumor necrosis factor-alpha antagonist in murine bone resorption model.C.N.R Alles, A.H Mian, N.S Soysa, H.Saito, K.Aoki, K.Akiyoshi, K.Ohya (2007). 29th Annual Meeting of American Society for Bone and Mineral Research (ASBMR), Hawaii, USA.

  44. The protecting role of TNFR2 on bone resorption. Mian M, Aoki K, Alles N, Soysa N, Nagano K, Ohya K (2007).The 49th Annual Meeting of The Japanese Society of Oral biology, Hokkaido, Japan.

  45. Applications of CHP Nanogel as a drug delivery system for tumor necrosis factor-alpha peptide antagonist in murine bone resorption model. C.N.R.A Alles, A.Mian, N.S. Soysa, K.Aoki, K.Akiyoshi, K.Ohya (2007).27th Annual Meeting of Japanese Society for Bone Morphometry, Nagasakii, Japan.

  46. The protecting role of TNFR2 on bone resorption. Mian M, Aoki K, Alles N, et al. (2007). 49th Annual Meeting of The JSOB, Sapporo, Japan.

  47. LPS-induced bone resorption is increased in TNFR2 KO mice in-vivo. M.H Mian, K Aoki, N Alles, et al. (2007). 55th Annual Meeting of JADR, Tsurumi, Japan.

  48. Inhibition of IKKb-NEMO binding blocks osteoclast activity and actin-ring formation. N.Soysa, C.Alles, H. Saito, K.Aoki, E.Jimi, K.Ohya (2006). 84th General Session and Exhibition of the International Association for Dental Research (IADR), Brisbane, Australia.

  49. Subcutaneous injection of W9 peptide and CHP nanogel complex inhibits the decrease of BMD induced by a low Ca feeding in mice. C.N.R.A Alles, N.Morimoto, U.Hasegawa, A.Mian, N.S. Soysa, H. Saito, K.Aoki, R.Baron, K.Akiyoshi, K.Ohya (2006).28th Annual Meeting American Society for Bone and Mineral Research (ASBMR), Philadelphia, Pennsylvania, USA.

  50. NEMO Binding Domain (NBD) peptide inhibits the activity of osteoclasts. N.Soysa, C.Alles, H. Saito, K.Aoki, E.Jimi, K.Ohya (2005). 53rd Annual meeting Japanese Association for Dental Research, Okayama, Japan.
Presentations at Local scientific meetings
  1. Attitudes towards complementaryand alternative medicine among medical students in Sri Lanka: Aa pilot study. S. Bandara, N Alles, N.S. Soysa, (2012). Annual research session-University of Peradeniya, Sri Lanka.

  2. Pharmacological suppression of NFkB increases bone formation in vitro and in vivo. NS Soysa, N Alles, (2010). 32nd Asia pacific dental congress, BMICH, Colombo, Sri Lanka.

  3. A novel IKK-β inhibitor S1627 blocks osteoclastogenesis and bone resorbing activity in vitro and in vivo. NS Soysa, N Alles, K.Aoki, K.Ohya (2010). , Sri Lanka.

  4. Deletion of precursor P100 not P52 cause osteopenia in mice. NS Soysa, N Alles, K.Aoki, K.Ohya (2010).Annual research session-University of Peradeniya, Sri Lanka.
 
Any other particulars
Research expertise
  • Strong background in animal models, histopathology and histomorphometry (bone densitometry (DEXA, pQCT), bone imaging (X-ray, microCT)).
  • Standard molecular and biological techniques.
  • Cell culture, molecular biology, and signaling.
  • Design and execute experiments, collect and analyze data.
Technical Expertise
  • Highly skilled in soft wares like MS word, MS Excel, MS power point, Stat view, Photoshop, End note ect.
  • Highly skilled in Computer System Design.
Leadership and Mentoring
  • The ability to motivate, lead, and/or supervise the activities of others.
  • Effective communication (both written and oral) and problem solving skills.
Interpersonal Skills
  • Work as part of a team, frequently interacting with different people and working across projects.
Other interests
  • Reading books.
  • Photography.
 
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