Dr. Keerthie Dissanayake
Senior Lecturer in Anatomy / Head of the Department
 
International Indexed Journals
  1. Hart, A.R.; Khan, N.L.A.; Dissanayake, K.; Godakumara, K.; Andronowska, A.; Eapen, S.; Heath, P.R.; Fazeli, A. The Extracellular Vesicles Proteome of Endometrial Cells Simulating the Receptive Menstrual Phase Differs from That of Endometrial Cells Simulating the Non-Receptive Menstrual Phase. Biomolecules 2023, 13, 279. https://doi.org/10.3390/biom13020279

  2. Piibor J, Dissanayake K, Midekessa G, Andronowska A, Kavak A, Waldmann A, Fazeli A. Characterization of bovine uterine fluid extracellular vesicles proteomic profiles at follicular and luteal phases of the oestrous cycle. Vet Res Commun. 2022 Dec 22. http://doi.org/ 10.1007/s11259-022-10052-3

  3. Reshi QUA, Godakumara K, Ord J, Dissanayake K, Hasan MM, Andronowska A, Heath P, Fazeli A. Spermatozoa, acts as an external cue and alters the cargo and production of the extracellular vesicles derived from oviductal epithelial cells in vitro. J Cell Commun Signal. 2022 Dec 5. http://doi.org/10.1007/s12079-022-00715-w

  4. Dissanayake K, Jayasinghe C, Wanigasekara P, Dissanayake J, Sominanda A. Validity of clinical disease activity index (CDAI) to evaluate the disease activity of rheumatoid arthritis patients in Sri Lanka: A prospective follow up study based on newly diagnosed patients. PLoS One. 2022 Nov 29;17(11):e0278285. http://doi.org/10.1371/journal.pone.0278285

  5. Hart AR, Khan NLA, Godakumara K, Dissanayake K, Piibor J, Muhandiram S, Eapen S, Heath PR, Fazeli A. The role of extracellular vesicles in endometrial receptivity and their potential in reproductive therapeutics and diagnosis. Reprod Biol. 2022 Jun;22(2):100645. http://doi.org/10.1016/j.repbio.2022.100645

  6. Godakumara, K., Dissanayake, K., Hasan, M. M., Kodithuwakku, S. P., & Fazeli, A. (2022). Role of extracellular vesicles in intercellular communication during reproduction. Reproduction in Domestic Animals, 57(Suppl. 5), 14–21. https://doi.org/10.1111/rda.14205

  7. Aleksejeva E, Zarovni N, Dissanayake K, Godakumara K, Vigano P, Fazeli A, Jaakma Ü, Salumets A. Extracellular vesicle research in reproductive science: Paving the way for clinical achievements†. Biol Reprod. 2022 Mar 19;106(3):408-424. http://doi.org/10.1093/biolre/ioab245

  8. Hasan MM, Reshi QUA, Lättekivi F, Viil J, Godakumara K, Dissanayake K, Andronowska A, Jaakma Ü, Fazeli A. Bovine Follicular Fluid Derived Extracellular Vesicles Modulate the Viability, Capacitation and Acrosome Reaction of Bull Spermatozoa. Biology (Basel). 2021 Nov 9;10(11):1154. http://doi.org/ 10.3390/biology10111154

  9. Midekessa G, Godakumara K, Dissanayake K, Hasan MM, Reshi QUA, Rinken T, Fazeli A. Characterization of Extracellular Vesicles Labelled with a Lipophilic Dye Using Fluorescence Nanoparticle Tracking Analysis. Membranes (Basel). 2021 Oct 12;11(10):779. http://doi.org/10.3390/membranes11100779

  10. Godakumara K, Ord J, Lättekivi F, Dissanayake K, Viil J, Boggavarapu NR, Faridani OR, Jääger K, Velthut-Meikas A, Jaakma Ü, Salumets A, Fazeli A. Trophoblast derived extracellular vesicles specifically alter the transcriptome of endometrial cells and may constitute a critical component of embryo-maternal communication. Reprod Biol Endocrinol. 2021 Jul 21;19(1):115. http://doi.org/10.1186/s12958-021-00801-5

  11. Dissanayake K, Nõmm M, Lättekivi F, Ord J, Ressaissi Y, Godakumara K, Reshi QUA, Viil J, Jääger K, Velthut-Meikas A, Salumets A, Jaakma Ü, Fazeli A. Oviduct as a sensor of embryo quality: deciphering the extracellular vesicle (EV)-mediated embryo-maternal dialogue. J Mol Med (Berl). 2021 May;99(5):685-697. http://doi.org/10.1007/s00109-021-02042-w

  12. Dissanayake K, Jayasinghe C, Wanigasekara P, Sominanda A. Potential applicability of cytokines as biomarkers of disease activity in rheumatoid arthritis: Enzyme-linked immunosorbent spot assay-based evaluation of TNF-α, IL-1β, IL-10 and IL-17A. PLoS One. 2021 Jan 26;16(1):e0246111. http://doi.org/ 10.1371/journal.pone.0246111.

  13. Midekessa G, Godakumara K, Ord J, Viil J, Lättekivi F, Dissanayake K, Kopanchuk S, Rinken A, Andronowska A, Bhattacharjee S, Rinken T, Fazeli A. Zeta Potential of Extracellular Vesicles: Toward Understanding the Attributes that Determine Colloidal Stability. ACS Omega. 2020 Jun 30;5(27):16701-16710. http://doi.org/10.1021/acsomega.0c01582

  14. Dissanayake K, Nõmm M, Lättekivi F, Ressaissi Y, Godakumara K, Lavrits A, Midekessa G, Viil J, Bæk R, Jørgensen MM, Bhattacharjee S, Andronowska A, Salumets A, Jaakma Ü, Fazeli A. Individually cultured bovine embryos produce extracellular vesicles that have the potential to be used as non-invasive embryo quality markers. Theriogenology. 2020 Jun;149:104-116. http://doi.org/10.1016/j.theriogenology.2020.03.008
Sri Lankan Journals
  1. Dissanayake, K.P., Dissanayake, K., Etulgama, S.B. and Hettiarachchi, K., 2021. Flexible Fibreoptic Bronchoscopy Performed Through a Laryngeal Mask Airway (FFB-LMA) in a Paediatric Population: Experience of a Tertiary Care Children's Hospital in Sri Lanka. Sri Lankan Journal of Anaesthesiology, 29(2), pp.88–94. http://doi.org/10.4038/slja.v29i2.8693
Book Chapters – Indexed
  1. Dissanayake K, Midekessa G, Lättekivi F, Fazeli A. Measurement of the Size and Concentration and Zeta Potential of Extracellular Vesicles Using Nanoparticle Tracking Analyzer. Methods Mol Biol. 2021;2273:207-218. https://doi.org/10.1007/978-1-0716-1246-0_15. PMID: 33604856.

  2. Reshi QUA, Hasan MM, Dissanayake K, Fazeli A. Isolation of Extracellular Vesicles (EVs) Using Benchtop Size Exclusion Chromatography (SEC) Columns. Methods Mol Biol. 2021;2273:201-206. https://doi.org/10.1007/978-1-0716-1246-0_14. PMID: 33604855.

  3. Dissanayake K, Midekessa G, Lättekivi F, Fazeli A. Measurement of the Size and Concentration and Zeta Potential of Extracellular Vesicles Using Nanoparticle Tracking Analyzer. Methods Mol Biol. 2021;2273:207-218. https://doi.org/10.1007/978-1-0716-1246-0_15. PMID: 33604856.
Abstract presentations at scientific meetings
International
  1. Dissanayake K, Godakumara K,  Muhandiram S, Fazeli A, Extracellular vesicle-mediated embryo maternal communication; Can only mothers respond when embryos talk?; Fertility 2022 Online Conference January 5-8; abstract number SP2E.4. https://www5.shocklogic.com/client_data/pp/uploads/2022/fertility/online/Short-paper-abstract-book.pdf

  2. Dissanayake K, Nõmm M, Lättekivi F, Ord J, Ressaissi Y, Godakumara K, et al., Oviduct as a sensor of embryo quality: deciphering the extracellular vesicle (EV) mediated embryomaternal dialogue; Fertility 2021 Online Conference January 6-10; abstract number P125. https://fertilityconference.org/wp-content/uploads/2021/01/Fertility-2021-Abstract-book_with-deleted-ones.pdf

  3. Dissanayake K, Nõmm M, Lättekivi F, Ressaissi Y, Godakumara K, Lavrits A, et al., Extracellular vesicles isolated from culture media conditioned by individually cultured bovine embryos as a potential embryo quality marker; Fertility 2020 January 9-11; Edingburgh, UK: abstract number P125. https://fertilityconference.org/wp-content/uploads/2020/03/Abstract-book.pdf

  4. Godakumara K, Es-haghi M, Dissanayake K, Lättekivi F, Salumets A, Jaakma Ü, Fazeli A, Deciphering embryo-maternal communication; the dynamics of first contact between progenitor and progeny; ISEV 2019, Abstract number PT02.04. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493311/pdf/zjev-8-1593587.pdf

  5. Midekessaa GB, Godakumara K, Reimann E, Viil J, Lättekivi J, Dissanayake K, Kopanchuk S, Thurston, L, Ebbens S, Rinken A, Rinken A, Fazeli A,; The effect of antibody binding on the zeta potential of extracellular vesicles secreted by cultured human choriocarcinoma cells; ISEV 2019, Abstract number PT02.04. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6493311/pdf/zjev-8-1593587.pdf

  6. Dissanayake K, Nõmm M, Tankov S, Lättekivi F, Lavrits A, Godakumara K, Viil J, Salumets A, Jaakma Ü, Fazeli A Single bovine embryo-derived extracellular vesicles: a potential biomarker of embryo quality; UKEV Forum 2018, 11th of December 2018, University of Sheffield, UK

  7. Ressaissi Y,  Dissanayake K, Nõmm M, Viil J,  Salumets A, Jaakma Ü, Andronowska A, Loi P,  Fazeli A, Assessing the effects of bovine embryo-derived extracellular vesicles on the development of individually cultured bovine embryos;  The 3rd annual CelliFit annual meeting 2019 https://research.unite.it/retrieve/e0ebe23a-66f8-322a-e053-3a05fe0a0cd4/Poster%20CellFIT.pdf

  8. Dissanayake DRKC, Dissanayake JK, Sominanda HMA, Jayasinghe C, Discontinuation of disease modifying anti-rheumatoid drugs by newly diagnosed rheumatoid arthritis patients – the need of better patient education, International Journal of Rheumatic Diseases 2015; 18 (Suppl. 1): 4–138 2.

  9. Dissanayake DRKC, Dissanayake JK, Sominanda HMA, Jayasinghe C, Short term therapeutic response in newly diagnosed rheumatoid arthritis (RA) patients for conventional synthetic disease modifying anti-rheumatoid drugs (Cs-DMARDS), International Journal of Rheumatic Diseases 2015; 18 (Suppl. 1): 4–138 3.

  10. Dissanayake DRKC, Dissanayake JK, Wanigasekera WADPC, Jayasinghe C, Sominanda HMA, Comparison of clinical disease activity index (CDAI) and Disease activity score 28 (DAS 28) as composite measures to assess the disease activity in patients with Rheumatoid arthritis (RA) in Sri Lanka, Proceedings of the Peradeniya university international research sessions, Sri Lanka, 2016, Vol.20, pp130 4.

  11. Gamage SMK, Alahakoon AMBD, Dissanayake DRKC., Gunathilake R, Adikari SB, Wijeweera I, Sominanda HMA, Occurrence of Aquaporin 4 receptor antibodies in patients suggestive of Multiple Sclerosis, Proceedings of the Peradeniya university international research sessions, Sri Lanka, 2016, Vol.20, pp 156
Local
  1. Dissanayake DRKC, Dissanayake JK, Wanigasekera WADPC, Jayasinghe C, Sominanda HMA, IL-17A in Rheumatoid arthritis (RA) patients: correlation with disease activity. 39th Annual Academic Sessions of Kandy Society of Medicine (KSM) 2017. pp 41 10.

  2. Dissanayake DRKC, Dissanayake JK, Wanigasekera WADPC, Jayasinghe C, Sominanda HMA, pretreatment cytokine profiles of peripheral blood mononuclear cells (PBMC) in patients with rheumatoid arthritis (RA) –a preliminary study, 39th Annual Academic Sessions of Kandy Society of Medicine (KSM) 2017. pp 42

  3. Dissanayake DRKC, Dissanayake JK, Wanigasekera WADPC, Jayasinghe C, Sominanda HMA, Demographic, clinical and paraclinical characteristics of newly diagnosed rheumatoid arthritis patients at a Rheumatology clinic in Sri Lanka, 38th Annual Academic Sessions of Kandy Society of Medicine (KSM) 2016. pp 125 9.

  4. Dissanayake DRKC, Dissanayake JK, Wanigasekera WADPC, Jayasinghe C, Sominanda HMA, Early and late therapeutic response for conventional synthetic disease modifying antirheumatic drugs (cs-DMARDs) in newly diagnosed rheumatoid arthritis (RA) patients, 38th Annual Academic Sessions of Kandy Society of Medicine (KSM) 2016. pp 44 8.

  5. Dissanayake DRKC, Neelawala WP, Dissanayake KP, Dissanayake JK, Sominanda HMA, Jayasinghe C, Impact of the disease activity and disease duration on activities of daily living in patients with rheumatoid arthritis, 37th Annual Academic Sessions of Kandy Society of Medicine (KSM) 2015. pp 39 7.

  6. Dissanayake DRKC, Jayasinghe C, Dissanayake DRKC, Sominanda HMA, Assesement of joint pain and disease activity in rheumatoid arthritis patients, Proceedings of the Peradeniya university research sessions, Sri Lanka, Vol.18, pp317 6.

  7. Ralapanawa DMPU, Dissanayake DRKC, Dissanayake CK, A case of vitamin B12 neuropathy in the absence of anaemia, 36th Annual Academic Sessions of Kandy Society of Medicine (KSM) 2014. pp 6 5.

  8. Dissanayake DRKC, Samarakoon MB, Ralapanawa DMPU, Inadequacy in notifying communicable diseases at a district base hospital , 36th Annual Academic Sessions of Kandy Society of Medicine (KSM) 2014. pp 64 4.

  9. Ralapanawa DMPU, Dissanayake DRKC, Basnayake BMPKD, Dissanayake CK, Awareness of diabetes mellitus in a rural setting , 36th Annual Academic Sessions of Kandy Society of Medicine (KSM) 2014. pp 15 3.

  10. Ralapanawa DMPU, Dissanayake DRKC, Dissanayake CK, Prevalence of overweight and obesity among patients with diabetes in a rural setting in Sri Lanka , 36th Annual Academic Sessions of Kandy Society of Medicine (KSM) 2014. pp 14 2.
 
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